🔥 NEXT ON GENERAL HOSPITAL — FRIDAY, NOVEMBER 21, 2025 | GH 11/21/25 SPOILERS ❤️🔥🕵️♂️
On the explosive November 21, 2025 episode of General Hospital, tensions erupt across Port Charles as secrets, betrayals, and long-buried truths surge to the surface, beginning with the chilling morning at General Hospital where Laura senses that something is terribly wrong after receiving an anonymous envelope containing a grainy photo of an unconscious patient she does not recognize, sparking fears that a dangerous figure from her past may have returned, and while she tries to keep calm, Kevin urges her to take extra precautions, unknowingly stepping directly into the chaos that is about to hit the hospital; meanwhile, in the dimly lit corridors of the PCPD, Dante grows increasingly uneasy after reviewing surveillance footage showing a shadowy figure lingering near the evidence room, and as he pieces together clues, he begins to suspect that someone inside the department may be tampering with files connected to the investigation surrounding the mysterious explosions at the old waterfront warehouse, prompting him to confront Chase, who is equally alarmed and vows to help him uncover the truth even if it means going against a superior officer; across town, Nina finds herself spiraling after overhearing a hushed conversation between Valentin and Martin about a sealed court document, leading her to worry that yet another secret related to Charlotte’s past may be on the verge of coming out, and in her desperation she decides to confront Valentin directly, demanding to know what he has been hiding from her this time, but Valentin, torn between protecting his daughter and maintaining whatever fragile trust remains between them, refuses to reveal the truth, leaving Nina furious and determined to uncover it on her own; at the Metro Court, Carly is blindsided when Josslyn rushes in with the shocking news that Adam has suddenly gone missing from his dorm after reportedly receiving a threatening message from an unknown number, and Carly, sensing a brewing danger reminiscent of past traumas involving kidnappings and stalking, immediately calls Sonny, who arrives with grave composure, promising to use his resources to track Adam down while simultaneously dealing with escalating tension in his organization as Brick informs him that a rival syndicate may have breached the city limits, raising the possibility that Adam’s disappearance is connected to a larger criminal plot; back at General Hospital, Liz grows suspicious when she notices that a recently admitted patient is using an alias she recognizes from a case years ago involving identity fraud, and when she brings her concerns to Finn, he advises her to keep quiet until they gather more information, but his reaction hints that he knows far more than he is saying, leaving Liz torn between following protocol and protecting patients who may be in danger; elsewhere, Trina and Spencer share a rare peaceful moment at the gallery while discussing their future, but their conversation is abruptly interrupted when Trina receives an urgent call from Taggert warning her to stay away from the waterfront due to an active police operation involving a dangerous fugitive connected to recent crimes, sparking Spencer’s protective instincts as he insists on staying by her side no matter what unfolds; in a secluded cabin outside Port Charles, Ava confronts a masked intruder who has been stalking her property for days, and after a tense standoff she manages to rip off the mask, revealing a shocking face from her past she believed long gone—Nikolas, who claims he has returned with proof that someone powerful in Port Charles framed him for crimes he did not commit, but his unstable demeanor leaves Ava uncertain whether to believe him or call the authorities, especially when he warns her that if she does, she could be the next target of the person who tried to destroy him; back at the hospital, tensions escalate when the power suddenly flickers, sending staff and patients into mild panic as emergency generators struggle to activate, prompting Laura to fear that the mysterious envelope she received earlier was a warning of sabotage, and her fears intensify when she notices that the photo from the envelope is missing from her office, indicating that someone has been inside without her knowledge; meanwhile, Sam and Jason, following a trail of cryptic clues connected to the warehouse explosion, discover that a shell corporation recently purchased property tied to a name Jason remembers from his time working for Sonny—a name associated with betrayal, violence, and unfinished business—and as they realize the threat may be far bigger than they imagined, they prepare themselves for a long night of dangerous revelations; the episode races toward its cliffhanger when Sonny receives a chilling video showing Adam tied to a chair in a dark room with a distorted voice warning that the sins of Port Charles’ most powerful families will soon be repaid, followed by a countdown clock and a demand that Sonny meet alone at Pier 47 before midnight, and as Carly watches the video in horror, Sonny vows he will end this threat once and for all, even as Dante discovers that the same shadowy figure seen at the PCPD has ties to the latest mob war brewing in the city, setting the stage for a night that promises to push every character to the breaking point as the clock ticks toward a confrontation that could change Port Charles forever.